Soft Vibrational Modes Predict Breaking Events during Force-Induced Protein Unfolding
نویسندگان
چکیده
منابع مشابه
Steered molecular dynamics simulations of force-induced protein domain unfolding.
Steered molecular dynamics (SMD), a computer simulation method for studying force-induced reactions in biopolymers, has been applied to investigate the response of protein domains to stretching apart of their terminal ends. The simulations mimic atomic force microscopy and optical tweezer experiments, but proceed on much shorter time scales. The simulations on different domains for 0.6 nanoseco...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.3781